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Coevolution With Spatially Structured Rice Landraces Maintains Multiple Generalist Lineages In The Rice Blast Pathogen

Ali, S.; Gladieux, P.; Ravel, S.; Adreit, H.; Meusnier, I.; Milazzo, J.; Cross-Arteil, S.; Bonnot, F.; Jin, B.; Dumartinet, T.; Charriat, F.; Lassangne, A.; He, X.; Tharreau, D.; Huang, H.; Morel, J.-B.; Fournier, E.

2021-12-16 evolutionary biology
10.1101/2021.12.15.472812 bioRxiv
Show abstract

Traditional agrosystems, where humans, crops and microbes have coevolved over long periods, can serve as models to understand the eco-evolutionary determinants of disease dynamics and help the engineering of durably resistant agrosystems. Here, we investigated the genetic and phenotypic relationship between rice (Oryza sativa) landraces and their rice blast pathogen (Magnaporthe oryzae) in the traditional Yuanyang terraces of flooded rice paddies in China, where rice landraces have been grown and bred over centuries without significant disease outbreaks. Analyses of genetic subdivision revealed that indica rice plants clustered according to landrace names. Three new diverse lineages of rice blast specific to the Yuanyang terraces coexisted with lineages previously detected at the worldwide scale. Population subdivision in the pathogen population did not mirror pattern of population subdivision in the host. Measuring the pathogenicity of rice blast isolates on landraces revealed generalist life histories. Our results suggest that the implementation of disease control strategies based on the emergence or maintenance of a generalist lifestyle in pathogens may sustainably reduce the burden of disease in crops.

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