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Identification and application of plasmatic microRNA expression quantitative trait loci (miR-QTL) at first trimester of pregnancy
2021-12-06
genetic and genomic medicine
Title + abstract only
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BackgroundMicroRNAs (miRNAs) are a class of small non-coding RNAs regulating gene expression. They are involved in many biological processes, including adaptation to pregnancy. The identification of genetic variants associated with gene expression, known as expression quantitative trait loci (eQTL), helps to understand the underlying molecular mechanisms and determinants of complex diseases. Using data from the prospective pre-birth Gen3G cohort, we investigated associations between maternal gen...
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