Inhibitory Cerebellar Stimulation Increases Cortical Activation: Evidence for Cerebellar Scaffolding of Cortical Processing
Maldonado, T.; Bernard, J. A.; Jackson, T. B.
Show abstract
While the cerebellum makes known contributions to non-motor task performance, the role of the structure remains unknown. One possibility is that the cerebellum allows for the offloading of cortical processing, providing support during task performance, using internal models. The current work used transcranial direct current stimulation to modulate cerebellar function and investigate the impact on cortical activation patterns. Participants received stimulation over the right cerebellum before a functional magnetic resonance imaging scan where participants completed a sequence learning and a working memory task. We predicted that cathodal stimulation would improve, and anodal stimulation would hinder task performance and cortical activation. We found that anodal cerebellar stimulation resulted in increased bilateral cortical activation, particularly in parietal and frontal regions known to be involved in cognitive processing. This suggests that if the cerebellum is not functioning optimally, there is a greater need for cortical resources.
Matching journals
The top 8 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Prefrontal stimulation prior to motor sequence learning alters multivoxel patterns in the striatum and the hippocampus 96%
- Improved correspondence of fMRI visual field localizer data after cortex-based macroanatomical alignment 95%
- Cortical sensorimotor activity in the execution and suppression of discrete and rhythmic movements 95%
Similar papers in this journal
- tDCS modulates effective connectivity during motor command following; a potential therapeutic target for disorders of consciousness 96%
- Beneficial effects of cerebellar tDCS on motor learning are associated with altered putamen-cerebellar connectivity: a simultaneous tDCS-fMRI study 96%
- Mapping Cognitive Brain Functions at Scale 95%
Similar papers in this journal
Similar papers in this journal
- Stimulating prefrontal cortex facilitates training transfer by increasing representational overlap 98%
- Enhancing Retrieval Capacity of the Predictive Brain through Dorsolateral Prefrontal Cortex Intervention 96%
- Frontal theta synchronization facilitates the updating of statistical regularities, evidenced by predictive eye movements 94%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.