Copper microRNAs govern the formation of giant feeding cells induced by the root knot nematode Meloidogyne incognita in Arabidopsis thaliana
Jaubert, S.; Noureddine, Y.; FAVERY, B.; QUENTIN, M.; Abad, P.; da Rocha, M.; Thomine, S.
Show abstract
miR408 and miR398 are two conserved microRNAs which expression is activated by the SPL7 transcription factor in response to copper starvation. We identified these two microRNAs families as upregulated in Arabidopsis thaliana and Solanum lycopersicum roots infected by root-knot nematodes. These endoparasites induce the dedifferentiation of a few root cells and the reprogramming of their gene expression to generate giant feeding cells. By combining functional approaches, we deciphered the signaling cascade involving these microRNAs, their regulator and their targets. MIR408 expression was located within nematode-induced feeding cells in which it co-localised with SPL7 expression and was regulated by copper. Moreover, infection assays with mir408 and spl7 KO mutants or lines expressing targets rendered resistant to cleavage by miR398 demonstrated the essential role of the SPL7/MIR408/MIR398 module in the formation of giant feeding cells. Our findings reveals how perturbation of plant copper homeostasis, via the SPL7/MIR408/MIR398 module, governs the formation of nematode-induced feeding cells.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Arabidopsis thaliana Zn2+-efflux ATPases HMA2 and HMA4 are required for resistance to the necrotrophic fungus Plectosphaerella cucumerina BMM 96%
- The role of AUX1 during lateral root development in the domestication of the model C4 grass Setaria italica 95%
- The role of CLV signalling in the negative regulation of mycorrhizal colonisation and nitrogen response of tomato 95%
Similar papers in this journal
- Root architecture plasticity in response to endoparasitic cyst nematodes is mediated by damage signaling 96%
- The phagocytosis oxidase/Bem1p (PB1) domain-containing protein PB1CP negatively regulates the NADPH oxidase RBOHD in plant immunity 94%
- Rhizobial infection-specific accumulation ofphosphatidylinositol 4,5-bisphosphate inhibits the excessive infection of rhizobia in Lotus japonicus 94%
Similar papers in this journal
- Transcriptomic analysis of resistant and susceptible responses in a new model root-knot nematode infection system using Solanum torvum and Meloidogyne arenaria 96%
- Tml1 And Tml2 Synergistically Regulate Nodulation And Affect Arbuscular Mycorrhiza In Medicago Truncatula 95%
- The Arabidopsis ATP-Binding Cassette E protein ABCE2 is a conserved component of the translation machinery 95%
Similar papers in this journal
Similar papers in this journal
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.