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Multi-ancestry gene-trait connection landscape using electronic health record (EHR) linked biobank data

2021-10-26 genetic and genomic medicine Title + abstract only
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Understanding genetic factors of complex traits across ancestry groups holds a key to improve the overall health care quality for diverse populations in the United States. In recent years, multiple electronic health record-linked (EHR-linked) biobanks have recruited participants of diverse ancestry backgrounds; these biobanks make it possible to obtain phenome-wide association study (PheWAS) summary statistics on a genome-wide scale for different ancestry groups. Moreover, advancement in bioinfo...

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