Integrated Genomic Surveillance reveals extensive onward transmission of travel-imported SARS-CoV-2 infections in the community
Houwaart, T.; Belhaj, S.; Tawalbeh, E.; Nagels, D.; Finzer, P.; Stiller, L.; Blum, J.; Lange, C.; Fröhlich, Y.; Benmoumene, A.; Asskali, D.; Haidar, H.; von Dahlen, J.; Adelmann, C.; Schroer, B.; Osmers, U.; Grice, C.; Kirfel, P. P.; Jomaa, H.; Pigulla, M.; Kreuzer, P.; Tyshaieva, A.; Weber, J.; Strelow, D.; Nicolai, J.; Wienemann, T.; Kohns Vasconcelos, M.; Hülse, L.; Hoffmann, K.; Lübke, N.; Hauka, S.; Andree, M.; Scholz, C. J.; Jazmati, N.; Göbels, K.; Zotz, R.; Pfeffer, K.; Timm, J.; Ehlkes, L.; Walker, A.; Dilthey, A. T.; German COVID-19 OMICS Initiative (DeCOI),
Show abstract
Integration of genomic surveillance with contact tracing provides a powerful tool for the reconstruction of person-to-person pathogen transmission chains. We report two large clusters of SARS-CoV-2 cases ("Delta" clade, 110 cases combined) detected in July 2021 by Integrated Genomic Surveillance in Dusseldorf. Structured interviews and deep contact tracing demonstrated an association to a single SARS-CoV-2 infected return traveller (Cluster 1) and to return travel from Catalonia and other European countries (Cluster 2), highlighting the importance of containing travel-imported SARS-CoV-2 infections.
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