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Brain Injury Localization in Electromagnetic Imaging using Symmetric Crossing Lines Method

Zhu, G.; Bialkowski, A.; Crozier, S.; Guo, L.; Nguyen, P.; Stancombe, A.; Abbosh, A.

2021-09-24 biophysics
10.1101/2021.09.22.461428 bioRxiv
Show abstract

To avoid death or disability, patients with brain injury should undertake a diagnosis at the earliest time and accept frequent monitoring after starting any medical intervention. This paper presents a novel approach to localize brain injury using the intersection of pairs of signals from symmetrical antennas based on the hypothesis that healthy brains are approximately symmetric that the bleeding targets will lead to significantly different amplitude and phase changes if one of pair of transmit signals cross targets. The scattered signals (S-parameters) are acquired using 100 realistic brain models and 150 experimental data measurements. Firstly, three pair of horizontal antennas are used to detect target crossing which line and in which hemisphere in low frequency bands and estimate the size using high frequency bands. Then, an intersection of two pairs of antennas are identified the position of the target. Finally, a heat map is used to visualise the stroke brain. The results indicate that crossing pairs of antenna signals from the hemisphere with a blood mass exhibit significantly different signal amplitude in the graph features compared to those without the target (p<0.003). The experiments show that our novel localization algorithm can achieve an accuracy of 0.85{+/-}0.08 Dice similarity coefficient based on 150 experimental measurements using an elliptical container, which is suitable for brain injury localization.

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