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Spread of SARS-CoV-2 Delta variant infections bearing the S:E484Q and S:T95I mutations in July and August 2021 in France

Verdume, L.; Danesh, G.; Trombert, S.; Sofonea, M. T.; Noel, V.; Foulongne, V.; Montes, B.; TUAILLON, E.; Haim-Boukobza, S.; Roquebert, B.; Alizon, S.

2021-09-16 epidemiology
10.1101/2021.09.13.21263371 medRxiv
Show abstract

Analysing 92,598 variant screening tests performed on SARS-CoV-2 positive samples collected in France between 1 July and 31 August 2021 shows an increase of Kappa-like infections. Full genome sequencing reveals that these correspond to Delta variants bearing the S:E484Q mutation. Most of these sequences belong to a phylogenetic cluster and also bear the S:T95I mutation. Further monitoring is needed to determine if this trend is driven by undocumented superspreading events or an early signal of future viral evolutionary dynamics.

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