TOR kinase controls shoot development by translational regulation of cytokinin catabolic enzymes
Janocha, D.; Pfeiffer, A.; Dong, Y.; Novak, O.; Strnad, M.; Ryabova, L.; Lohmann, J. U.
Show abstract
Plants continuously adjust their developmental program including organ initiation and growth in accordance with endogenous and environmental signals. This plasticity requires that a diversity of signaling pathways acts in concert to modulate stem cell activity. We have shown previously that the TOR kinase network integrates metabolic- and light signals and controls expression of WUSCHEL, a transcriptional master regulator of stem cells in the shoot apical meristem. However, the mechanism linking TOR activity with the WUSCHEL promoter remained unresolved. Here we demonstrate that TOR regulates the accumulation of trans-zeatin, the cytokinin species mainly responsible for shoot development. Importantly, we identify translational repression of RNAs encoding cytokinin degrading CYTOKININ OXIDASES/DEHYDROGENASE enzymes by TOR as an underlying mechanism. Employing this system, plants can quickly adjust stem cell activity and developmental programs in response to changes in their environment.
Matching journals
The top 4 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Light activates the translational regulatory GCN2 kinase via reactive oxygen species emanating from the chloroplast 97%
- Arabidopsis Casein Kinase 2 triggers Stem Cell Exhaustion under Al Toxicity and Phosphate Deficiency Through activation of the DNA Damage Response pathway 97%
- Constitutive activation of leucine-rich repeat receptor kinase signaling pathways by BAK1-interacting receptor-like kinase 3 chimera 96%
Similar papers in this journal
- ETHYLENE RESPONSE FACTOR 115 integrates jasmonate and cytokinin signaling machineries to repress adventitious rooting in Arabidopsis 98%
- A Phosphorus-Limitation Induced, Functionally Conserved DUF506 Protein is a Repressor of Root Hair Elongation in Arabidopsis thaliana 97%
- A plastidial retrograde-signal potentiates biosynthesis of systemic stress response activators 97%
Similar papers in this journal
- Jasmonate inhibits adventitious root initiation through transcriptional repression of CKX1 and activation of RAP2.6L transcription factor in Arabidopsis 98%
- MYB12 spatiotemporally represses TMO5/LHW-mediated transcription in the Arabidopsis root meristem 97%
- PYL8 ABA receptors of Phoenix dactylifera play a crucial role in response to abiotic stress and are stabilized by ABA 96%
Similar papers in this journal
- A network of RS splicing regulatory proteins controls light-dependent splicing and seedling development 97%
- Arabidopsis lines with modified ascorbate concentrations reveal a link between ascorbate and auxin biosynthesis 97%
- Diphthamide formation in Arabidopsis requires DPH1-interacting DPH2 for light and oxidative stress resistance 96%
Similar papers in this journal
- Unbiased proteomic and forward genetic screens reveal that mechanosensitive ion channel MSL10 functions at ER-plasma membrane contact sites in Arabidopsis thaliana 96%
- The Arabidopsis SAC9 Enzyme is enriched in a cortical population of early endosomes and restricts PI(4,5)P2 at the Plasma Membrane 96%
- A ppGpp-mediated brake on photosynthesis is required for acclimation to nitrogen limitation in Arabidopsis. 96%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.