Characterization of glucosyltransferase and glucuronosyltransferase family members reveals how major flavone glycoside accumulate in the root of Scutellaria baicalensis
Pei, T.; Li, T.; Li, X.; Yin, Y.; Cui, M.; Fang, Y.; Liu, J.; Kong, Y.; Xu, P.; Zhao, Q.
Show abstract
Flavonoid glycosides extracted from roots of Scutellaria baicalensis exhibit strong pharmaceutical effect in antitumor, antioxidative, anti-inflammatory, and antiviral activity. UDP glycosyltransferase family members are responsible for the transfer of a glycosyl moiety from UDP sugars to a wide range of acceptor flavonoids. Here, we report the phylogenetic analysis, tissue-specific expression and biochemical characterization of 10 glucosyltrasferases (SbUGTs) and 6 glucuronosyltransferases (SbUGATs) based on the recently released genome of S. baicalensis. These results reveal that the high expression level and affinity to substrate of SbUGAT4 make baicalin become the richest flavonoid glycoside in the root of S. baicalensis.
Matching journals
The top 7 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- MeSSII interplays the amylose and amylopectin biosynthesis by protein interactions in cassava storage root 93%
- OsCYP71D8L as a key regulator involved in growth and stress response by mediating gibberellins and cytokinins homeostasis in rice 93%
- Arabidopsis CPK6 regulates drought tolerance under high nitrogen by the phosphorylation of NRT1.1 93%
Similar papers in this journal
- Systematic analysis of the R2R3-MYB family of transcription factors in Camellia sinensis: evidence for species-specific catechin biosynthesis regulation 95%
- miRNA858b Inhibits Proanthocyanidin Accumulation by Repression of DkMYB19 and DkMYB20 in Persimmon 95%
- Unveiling unique metabolomic and transcriptomic profiles in three Brassicaceae crops 94%
Similar papers in this journal
- CRISPR/Cas9-mediated genome editing reveals the involvement of a polyphenol oxidase in the shikonin-specific biosynthesis in Lithospermum erythrorhizon 94%
- Radicle growth regulation of root parasitic plants by auxin-related compounds 93%
- Apoplast-localized β-Glucosidase Elevates Isoflavone Accumulation in the Soybean Rhizosphere 93%
Similar papers in this journal
- The natural tannins oligomeric proanthocyanidins and punicalagin are potent inhibitors of infection by SARS-CoV-2 in vitro 93%
- Structure and evolution of Alanine/Serine Decarboxylases and the engineering of theanine production 92%
- A beta-glucosidase of an insect herbivore determines both toxicity and deterrence of a dandelion defense metabolite 92%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.