Back

The Anorexia Nervosa Care Pathway: Closing the Treatment Gap to Improve Care for Patients Admitted to Medical Hospitals

Allen, K.; O Brien, K.; O'Reilly, M.; Henderson, D.; Machale, S.; Boland, K.

2021-06-21 nutrition
10.1101/2021.06.14.21258873 medRxiv
Show abstract

IntroductionMedical complications of malnutrition and refeeding account for approximately half of deaths in anorexia nervosa (AN). The AN Care Pathway (ANCP) was introduced at our institution in 2016 to improve quality of care of patients admitted for medical observation and management. We report results from our review of medical complications and report the impact and adoption of the ANCP. MethodsThe ANCP was developed in response to a need to improve quality of medical monitoring of patients with severe AN using Squire Guidelines and the Plan-Do-Study-Act cycle. All patients admitted to a medical hospital with AN between 2010-2020 were included after hospital inpatient enquiry and medical records were reviewed. Descriptive statistics were calculated using Stata (Statcorp). ResultsFifty-one patients (63 admissions) were included. Median BMI was 13.8 kg/m (11.9-22.5). After ANCP implementation in 2016, compliance with recommended daily ECG, thiamine and blood tests improved from 30% (n=8/27) to 86% (n=21/36). We report a high rate of medical complications of severe AN including anaemia (n=24, 47%), neutropoenia (n=18, 35%), abnormal liver bloods (n=15, 29%) and half developed refeeding syndrome. One-third patients had cardiovascular compromise including reduced cardiac contractility (n=13, 25%), pericardial effusion (n=7, 14%) and one death. Low BMI was associated with cardiovascular complications (mean BMI 13.5 kg/m vs 15.5 kg/m, p=0.01) and neutropoenia (mean BMI 13.4 kg/m vs 15.4 kg/m, p=0.02). ConclusionIntroduction of the ANCP improved quality of care during medical stabilisation. We report a high rate of medical complications of severe AN in patients admitted to a medical hospital. Use of multidisciplinary care protocols may contribute to quality improvement and improved consistency of care for this vulnerable population.

Matching journals

The top 9 journals account for 50% of the predicted probability mass.

1
Psychiatry Research
35 papers in training set
Top 0.1%
19.3%
2
PLOS ONE
4510 papers in training set
Top 20%
9.5%
3
BMJ Public Health
18 papers in training set
Top 0.1%
5.0%
4
BMC Medical Informatics and Decision Making
39 papers in training set
Top 0.7%
4.1%
5
BMJ Open
554 papers in training set
Top 5%
3.7%
6
Healthcare
16 papers in training set
Top 0.2%
3.2%
7
Nutrients
64 papers in training set
Top 0.7%
2.7%
8
BMJ Nutrition, Prevention & Health
10 papers in training set
Top 0.1%
2.4%
9
Cureus
67 papers in training set
Top 2%
2.2%
50% of probability mass above
10
Journal of Clinical Medicine
91 papers in training set
Top 2%
2.2%
11
Journal of Global Health
18 papers in training set
Top 0.2%
2.0%
12
Frontiers in Pediatrics
29 papers in training set
Top 0.3%
1.8%
13
BMC Medicine
163 papers in training set
Top 4%
1.4%
14
Scientific Reports
3102 papers in training set
Top 63%
1.4%
15
Journal of Cachexia, Sarcopenia and Muscle
27 papers in training set
Top 0.2%
1.4%
16
Obesity
19 papers in training set
Top 0.3%
1.3%
17
Journal of Translational Medicine
46 papers in training set
Top 1%
1.3%
18
Emergency Medicine Journal
20 papers in training set
Top 0.4%
1.3%
19
Frontiers in Endocrinology
53 papers in training set
Top 1%
1.3%
20
Journal of Neurology, Neurosurgery & Psychiatry
29 papers in training set
Top 0.9%
1.3%
21
Metabolism
14 papers in training set
Top 0.3%
1.3%
22
Infection
15 papers in training set
Top 0.2%
1.3%
23
Influenza and Other Respiratory Viruses
44 papers in training set
Top 0.3%
1.3%
24
Frontiers in Psychology
49 papers in training set
Top 0.7%
1.3%
25
Public Health
34 papers in training set
Top 0.9%
1.3%
26
Journal of Clinical and Translational Science
11 papers in training set
Top 0.3%
1.3%
27
International Journal of Environmental Research and Public Health
124 papers in training set
Top 5%
1.0%
28
iScience
1063 papers in training set
Top 24%
1.0%
29
Public Health Nutrition
14 papers in training set
Top 0.5%
0.9%
30
PLOS Neglected Tropical Diseases
378 papers in training set
Top 5%
0.8%