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Direct observation of adaptive tracking on ecological timescales in Drosophila

Rudman, S. M.; Greenblum, S. I.; Rajpurohit, S.; Betancourt, N. J.; Hanna, J.; Tilk, S.; Yokoyama, T.; Petrov, D. A.; Schmidt, P.

2021-04-28 evolutionary biology
10.1101/2021.04.27.441526 bioRxiv
Show abstract

Direct observation of evolution in response to natural environmental change can resolve fundamental questions about adaptation including its pace, temporal dynamics, and underlying phenotypic and genomic architecture. We tracked evolution of fitness-associated phenotypes and allele frequencies genome-wide in ten replicate field populations of Drosophila melanogaster over ten generations from summer to late fall. Adaptation was evident over each sampling interval (1-4 generations) with exceptionally rapid phenotypic adaptation and large allele frequency shifts at many independent loci. The direction and basis of the adaptive response shifted repeatedly over time, consistent with the action of strong and rapidly fluctuating selection. Overall, we find clear phenotypic and genomic evidence of adaptive tracking occurring contemporaneously with environmental change, demonstrating the temporally dynamic nature of adaptation. One sentence summaryRapid environmental change drives continuous phenotypic and polygenic adaptation, demonstrating the temporal dynamism of adaptation.

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