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Impact of national and regional lockdowns on COVID-19 epidemic waves: Application to the 2020 spring wave in France

Roux, J.; Massonnaud, C.; Colizza, V.; Cauchemez, S.; Crepey, P.

2021-06-16 epidemiology
10.1101/2021.04.21.21255876 medRxiv
Show abstract

Several countries have implemented lockdowns to control their COVID-19 epidemic. However, questions like "where" and "when" still require answers. We assessed the impact of national and regional lockdowns considering the French first epidemic wave of COVID-19 as a case study. In a regional lockdown scenario aimed at preventing intensive care units (ICU) saturation, almost all French regions would have had to implement a lockdown within 10 days and 96% of ICU capacities would have been used. For slowly growing epidemics, with a lower reproduction number, the expected delays between regional lockdowns increases. However, the public health costs associated with these delays tend to grow exponentially with time. In a quickly growing pandemic wave, defining the timing of lockdowns at a regional rather than national level delays by a few days the implementation of a nationwide lockdown but leads to substantially higher morbidity, mortality and stress on the healthcare system.

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