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Pregnancy outcomes from a restorative infertility treatment model: a single centre case series

James, G.; McLindon, L. A.; Hatch, J.; Mol, B. W.; Turner, J.

2021-04-17 sexual and reproductive health
10.1101/2021.04.14.21251044 medRxiv
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BackgroundInfertility is a significant problem with multiple causes and a corresponding array of therapeutic options. In an era of increasing assisted reproductive treatments, few studies examine the role of conventional non-assisted reproductive treatments to address underlying behavioural, lifestyle and medical issues. AimTo assess outcomes from a conventional or non-assisted reproductive treatment approach Materials and MethodsRetrospective case series of 162 couples that attended an Australian, hospital-based, multidisciplinary fertility clinic between 2005 and 2010. ResultsThere were 58 live births for all couples giving a crude live birth rate of 35.4% over a 24-month analysis period. When adjusted by Kaplan-Meier method, a 57.4% cumulative live birth rate (CLBR) was achieved. Couples had a median 33.9 months duration of infertility and the median female age was 33.7. For the 74 couples with an unexplained infertility diagnosis, 32 achieved a live birth at a crude rate of 43.2% or 71.2% CLBR when adjusted by Kaplan-Meier method. ConclusionsThis observational data indicates that reproductive medicine should have a personalized approach in which alternatives for immediate IVF are considered.

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"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.