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Genomic epidemiology of SARS-CoV-2 in Russia reveals recurring cross-border transmission throughout 2020

Matsvay, A.; Klink, G. V.; Safina, K. R.; Nabieva, E.; Garushyants, S. K.; Biba, D.; Bazykin, G. A.; Mikhaylov, I. M.; Say, A. V.; Zakamornaya, A. I.; Khakhina, A. O.; Lisitsa, T. S.; Ayginin, A. A.; Abramov, I. S.; Bogdan, S. A.; Kolbutova, K. B.; Oleynikova, D. U.; Avdeenko, T. F.; Shipulin, G. A.; Yudin, S. M.; Skvortsova, V. I.

2021-04-06 epidemiology
10.1101/2021.03.31.21254115 medRxiv
Show abstract

SARS-CoV-2 has spread rapidly across the globe, with most nations failing to prevent or substantially delay its introduction. While many countries have imposed some limitations on trans-border passenger traffic, the effect of these measures on the spread of COVID-19 strains remains unclear. Here, we report an analysis of whole-genome sequencing of 3206 SARS-CoV-2 samples from 78 regions of Russia covering the period between March and November 2020. We describe recurring imports of multiple COVID-19 strains throughout this period, giving rise to 457 uniquely Russian transmission lineages, as well as repeated cross-border transmissions of local circulating variants out of Russia.

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