A novel whole-blood stimulation assay to detect and quantify memory T-cells in COVID-19 patients
Mouton, W.; Compagnon, C.; Saker, K.; Daniel, S.; Lacoux, X.; Pozzetto, B.; Oriol, G.; Djebali, S.; Berthier, F.; Marvel, J.; Walzer, T.; Brengel-Pesce, K.; Trouillet-Assant, S.; COVID-ser study group,
Show abstract
SARS-CoV-2 specific T-cells responses are essential for virus clearance. We present a novel and simple whole-blood assay allowing the detection of interferon-gamma-producing antiviral T-cells following peptide stimulation. We show that unlike neutralizing antibodies, antiviral memory T-cells persist at least 6 months in convalescent Covid-19 individuals.
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