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Manipulating vector transmission reveals local processes in bacterial communities of bats

McKee, C. D.; Webb, C. T.; Kosoy, M. Y.; Bai, Y.; Osikowicz, L. M.; Suu-Ire, R.; Ntiamoa-Baidu, Y.; Cunningham, A. A.; Wood, J. L.; Hayman, D. T.

2021-03-04 ecology
10.1101/2021.03.03.433743 bioRxiv
Show abstract

Infectious diseases result from multiple interactions among microbes and hosts, but community ecology approaches are rarely applied. Manipulation of vector populations provides a unique opportunity to test the importance of vectors in infection cycles while also observing changes in pathogen community diversity and species interactions. Yet for many vector-borne infections in wildlife, a biological vector has not been experimentally verified and few manipulative studies have been performed. Using a captive colony of fruit bats in Ghana, we observed changes in the community of Bartonella bacteria over time after the decline and subsequent reintroduction of bat flies. With reduced transmission, community changes were attributed to ecological drift and potential selection through interspecies competition mediated by host immunity. This work demonstrated that forces maintaining diversity in communities of free-living macroorganisms act in similar ways in communities of symbiotic microorganisms, both within and among hosts. Additionally, this study is the first to experimentally test the role of bat flies as vectors of Bartonella species.

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