Back

A proteomics workflow reveals predictive autoantigens in idiopathic pulmonary fibrosis

2021-02-19 respiratory medicine Title + abstract only
View on medRxiv
Show abstract

RationaleThe diagnosis of idiopathic pulmonary fibrosis (IPF) requires exclusion of known underlying autoimmunity, as present in interstitial lung diseases associated with connective tissue diseases (CTD-ILD). However, autoantibodies of unknown significance have been repeatedly detected in IPF patients. ObjectivesWe aimed to characterize autoreactivities in IPF patients beyond clinically established autoimmune panels by establishing an unbiased assay for de novo discovery of autoantigens in dif...

Predicted journal destinations