Phase-based cortical synchrony is affected by prematurity
Yrjölä, P.; Stjerna, S.; Palva, J. M.; Vanhatalo, S.; Tokariev, A.
Show abstract
Inter-areal synchronization by phase-phase correlations (PPC) of cortical oscillations mediates many higher neurocognitive functions, which are often affected by prematurity, a globally prominent neurodevelopmental risk factor. Here, we used electroencephalography (EEG) to examine brain-wide cortical PPC networks at term-equivalent age, comparing human infants after early prematurity to a cohort of healthy controls. We found that prematurity affected these networks in a sleep state-specific manner, and the differences between groups were also frequency-selective, involving brain-wide connections. The strength of synchronization in these networks was predictive of clinical outcomes in the preterm infants. These findings show that prematurity affects PPC networks in a clinically significant manner suggesting early functional biomarkers of later neurodevelopmental compromise to be used in clinical and translational studies after early neonatal adversity.
Matching journals
The top 3 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- Sleep modulates neural timescales and spatiotemporal integration in the human cortex 96%
- Coordination of human hippocampal sharpwave-ripples during NREM sleep with cortical theta bursts, spindles, downstates and upstates 96%
- The theta paradox: 4-8 Hz EEG oscillations reflect both local sleep and cognitive control 95%
Similar papers in this journal
- Sleep spindle maturation enhances slow oscillation-spindle coupling 96%
- Waveform detection by deep learning reveals multi-area spindles that are selectively modulated by memory load 95%
- Reproducible, data-driven characterization of sleep based on brain dynamics and transitions from whole-night fMRI 95%
Similar papers in this journal
- Spindle - slow oscillation coupling correlates with memory performance and connectivity changes in a hippocampal network after sleep 96%
- Investigating the spectral features of the brain meso-scale structure at rest 93%
- Functional connectome mediates the association between sleep disturbance and mental health in preadolescence 93%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.