A systematic approach for finding herbicide synergies
Sukhoverkov, K. V.; Mylne, J. S.
Show abstract
Combining herbicides into a double dose is a common approach to overcome the potential for herbicide resistance by weeds. Many herbicide mixtures can be antagonistic and they are rarely synergistic. Here, 24 commercial herbicides, each representing a mode of action were used to create a matrix of all 276 unique combinations to search for new synergies in agar with Arabidopsis thaliana. Herbicides were used at an appropriate sub-lethal dose such that any synergies gave visible growth inhibition. We found five synergies including three new ones, namely mesotrione-norflurazon, mesotrione-clethodim and paraquat-clomazone. All three new synergies were reproducible in soil-grown conditions. Interestingly, all three new combinations included a bleaching herbicide, suggesting synergy might be a class specific phenomenon. We also found that mesotrione-norflurazon and mesotrione-clethodim combinations remained synergistic against lettuce (Lactuca sativa), but not tef (Eragrostis tef). Our study shows that screening herbicide mixtures against A. thaliana is an efficient approach for finding rare herbicide synergies.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Multiple stressors in multiple species: effects of different RDX soil concentrations and differential water-resourcing on RDX fate, plant health, and plant survival 94%
- How to account for the uncertainty from standard toxicity tests in species sensitivity distributions: an example in non-target plants 94%
- Ser-653-Asn substitution in the acetohydroxyacid synthase gene confers resistance in weedy rice to imidazolinone herbicides imazapic and imazapyr in Malaysia 94%
Similar papers in this journal
- Recurrent selection with glufosinate at low rates reduces the susceptibility of a Lolium perenne ssp. multiflorum population to glufosinate 96%
- Gibberellins target shoot-root growth, morpho-physiological and molecular pathways to induce cadmium tolerance in mung bean 92%
- Impacts of environmental factors on seed germination and seedling emergence of white clover (Trifolium repens L.) 91%
Similar papers in this journal
Similar papers in this journal
- Nematicidal and antifeedant activity of ethyl acetate extracts from culture filtrates of Arabidopsis thaliana fungal endophytes 92%
- Risks of exposure to systemic insecticides in agricultural soil in Ontario, Canada for the hoary squash bee (Peponapis pruinosa) and other ground-nesting bee species 92%
- A phototaxis assay to measure sublethal effects of pesticides on bees 91%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.