Back

The humoral response to BK polyomavirus in kidney transplant recipients is dominated by IgM antibodies that use a distinct repertoire compared to IgG against the same antigen

2021-02-09 allergy and immunology Title + abstract only
View on medRxiv
Show abstract

1.The BK polyomavirus (BKPyV) persists asymptomatically in the kidney and active replication is only seen in immunosuppressed individuals, such as kidney transplant (KTx) recipients, in whom BKPyV reactivation can cause significant morbidity. KTx recipients with BKPyV reactivation mount a robust humoral response, but this often fails to clear the virus. In order to characterize the BKPyV-specific B-cell receptor (BCR) repertoire in KTx recipients, we used fluorescence-labeled BKPyV virus-like pa...

Predicted journal destinations

1
Nature Communications
483 training papers
Top 7% 11.5%
2
Frontiers in Immunology
140 training papers
Top 0.9% 9.1%
3
Journal of Clinical Investigation
50 training papers
#1 8.8%
4
Cell Reports Medicine
49 training papers
#1 6.3%
5
PLOS ONE
1737 training papers
Top 78% 5.8%
6
eLife
262 training papers
Top 5% 5.8%
7
JCI Insight
63 training papers
Top 1% 4.1%
8
Scientific Reports
701 training papers
Top 68% 3.8%
9
npj Vaccines
18 training papers
#1 3.8%
10
The Journal of Immunology
19 training papers
Top 0.3% 3.8%
11
Science Translational Medicine
40 training papers
Top 0.7% 1.9%
12
Science Immunology
15 training papers
Top 0.2% 1.9%
13
The Journal of Infectious Diseases
137 training papers
Top 9% 1.5%
14
iScience
74 training papers
Top 5% 1.5%
15
eBioMedicine
82 training papers
Top 3% 1.5%
16
Cell
28 training papers
Top 0.8% 1.5%
17
Journal of the American Society of Nephrology
19 training papers
Top 1% 1.5%
18
Vaccines
131 training papers
Top 8% 1.3%
19
Clinical Infectious Diseases
219 training papers
Top 20% 1.3%
20
Cancers
57 training papers
Top 6% 1.3%
21
Vaccine
140 training papers
Top 7% 1.1%
22
Cell Reports
25 training papers
Top 1% 1.1%
23
Cell Genomics
34 training papers
Top 6% 1.1%
24
Communications Biology
36 training papers
Top 3% 1.0%
25
Journal of Medical Virology
95 training papers
Top 12% 0.9%
26
Proceedings of the National Academy of Sciences
100 training papers
Top 16% 0.9%
27
Annals of the Rheumatic Diseases
23 training papers
Top 1% 0.7%
28
Nature Medicine
88 training papers
Top 19% 0.7%
29
mSphere
27 training papers
Top 2% 0.7%