Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum
Sapkal, G. N.; Yadav, P.; Ella, R.; Deshpande, G.; Sahay, R.; Gupta, N.; Mohan, V. K.; Abraham, P.; Panda, S.; Bhargava, B.
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We performed the plaque reduction neutralization test (PRNT50) using sera collected from the 26 recipients of BBV152/COVAXIN against hCoV-19/India/20203522 (UK-variant) and hCoV27 19/India/2020Q111 (heterologous strain). A comparable neutralization activity of the vaccinated individuals sera showed against UK-variant and the heterologous strain with similar efficiency, dispel the uncertainty of possible neutralization escape.
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