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Long range, high-gamma phase coherence in the human brain during overt and covert speech

Valiante, T.; Garic, B.

2021-01-23 neuroscience
10.1101/2021.01.23.427916 bioRxiv
Show abstract

Using intracranial electroencephalography (iEEG) in patients undergoing diagnostic workup for epilepsy, we show that during reading, phase coherent high-gamma activity emerges between spatially distant regions of proven involvement in vocalization. Using the novel metric of "phase-dependent power-causal correlations", causal interactions were shown to be maximal at high-gamma frequencies, and displayed stronger correlations to power fluctuations near the optimal time delay, with this delay potentially accounted for by axonal conduction. We conclude that high-gamma activity may represents propagated, directed, large-scale integration between task related regions of the human brain.

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