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Comparative Analysis Of Triplet Composition Of Common Mitochondrial And Chloroplast Genes Of The Same Species

Sadovsky, M. G.; Fedotovskaia, V.

2020-12-21 genomics
10.1101/2020.12.18.423570 bioRxiv
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We studied the relation between the genes encoding the same protein (ATP synthase) in mitochondria and chloroplasts, of the same species. 85 species are studied. The relation is revealed through the unsupervised clustering via elastic map implementation of the points in 64-dimensional space of the triplet frequencies of the genes. The triplet composition was counted with a nucleotide shift of the reading frame along a gene. Three types of clustering have been analyzed: for mitochondria genes solely, for chloroplast genes solely, and for the merged set of the genes from the genomes of both organellae. It was found that the encoded function is the feature in clustering: all the clusters in all three versions of clustering patterns clearly exhibit distinct separation of the genes encoding the same subunit into a separate cluster. This behaviour was found for all three types of cluster patterns.

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