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A new Petri Net Model of Working Memory to Predict the Root Causes of Attention Deficit Disorder Symptoms

Baghdadi, G.; Doustmohammadi, A.; Jamshidi, A.; Towhidkhah, F.

2020-12-11 neuroscience
10.1101/2020.12.10.419093 bioRxiv
Show abstract

Working memory is a system that helps us to store, retrieve, and manipulate information for a short period. The improper function of working memory is highly reported in people with attention deficit disorder. Attention deficit disorder is one of the most common disruptive behavioral disorders in children. Finding the actual reasons that may lead to inattentive symptoms is still an enigma for scientists. In this study, a model was proposed to show the flow of information through sensory, long-term, and working memory based on the Petri net approach. A new "selective updating" mechanism is also suggested. It is speculated that the central executive part of working memory uses this mechanism for updating the less important content with new incoming essential inputs. The analysis of the proposed model shows how an abnormality in the time setting or unexpected delays in information transmission may lead to some symptoms of inattention. These predictions about the possible causes of inattentive symptoms would be valuable for psychologists to find new possible treatments. This study also illustrates the great potential of Petri net approach for modeling and analysis of biological systems.

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