Enhancement of antimicrobial diversity in situ through relaxed symbiont specificity in an insect/actinomycete partnership
Pessotti, R. d. C.; Hansen, B. L.; Reaso, J. N.; Ceja-Navarro, J. A.; El-Hifnawi, L.; Brodie, E. L.; Traxler, M. F.
Show abstract
Some insects form symbioses in which actinomycetes provide defense against pathogens by making antimicrobials. The range of chemical strategies employed across these associations, and how these strategies relate to insect lifestyle, remains underexplored. We assessed subsocial passalid beetles of the species Odontotaenius disjunctus, and their frass (fecal material) which is an important food resource within their galleries, as a model insect/actinomycete system. Through chemical and phylogenetic analyses, we found that O. disjunctus frass collected across eastern North America harbored multiple lineages of Streptomyces and diverse antimicrobials. Metabolites detected in frass displayed synergistic and antagonistic inhibition of a fungal entomopathogen, Metarhizium anisopliae, and multiple streptomycete isolates inhibited this pathogen when co-cultivated directly in frass. These findings support a model in which the lifestyle of O. disjunctus accommodates multiple Streptomyces lineages in their frass, resulting in a rich repertoire of antimicrobials that likely insulates their galleries against pathogenic invasion.
Matching journals
The top 5 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Cycloheximide-Producing Streptomyces Associated with Xyleborinus saxesenii and Xyleborus affinis Fungus-Farming Ambrosia Beetles 96%
- Skin microbiomes of frogs vary among individuals and body regions, revealing differences that reflect known patterns of chytrid infection 94%
- Metagenomics reveals diet-specific specialization of bacterial communities in fungus gardens of grass- and dicot-cutter ants 93%
Similar papers in this journal
- Fungal seed pathogens of wild chili peppers possess multiple mechanisms to tolerate capsaicinoids 95%
- Microbial Associates of the Elm Leaf Beetle: Uncovering the Absence of Resident Bacteria and the Influence of Fungi on Insect Performance 94%
- Prevalence and correlates of phenazine resistance in culturable bacteria from a dryland wheat field 94%
Similar papers in this journal
- Hülle-cell-mediated protection of fungal reproductive and overwintering structures against fungivorous animals 94%
- Antimicrobials from a feline commensal bacterium inhibit skin infection by drug-resistant S. pseudintermedius. 94%
- Effects of parental care on skin microbial community composition in poison frogs 94%
Similar papers in this journal
- Toxin-producing endosymbionts shield pathogenic fungus against micropredators 96%
- Effects of agricultural fungicide use on Aspergillus fumigatus abundance, antifungal susceptibility, and population structure 94%
- Tornadic shear stress induces a transient, calcineurin-dependent hyper-virulent phenotype in Mucorales molds 93%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.