Recovering genomes and phenotypes using allele-specific gene expression
Gursoy, G.; Lu, N.; Wagner, S.; Gerstein, M.
Show abstract
With the recent increase in RNA sequencing efforts using large cohorts of individuals, studying allele-specific gene expression is becoming increasingly important. Here, we report that, despite not containing explicit variant information, a list of allele-specific gene names of an individual is enough to recover key variants and link the individual back to their genome or phenotype. This creates a privacy conundrum.
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