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SIPEC: the deep-learning Swiss knife for behavioral data analysis

Marks, M.; Qiuhan, J.; Sturman, O.; von Ziegler, L.; Kollmorgen, S.; von der Behrens, W.; Mante, V.; Bohacek, J.; Yanik, M. F.

2020-10-26 neuroscience
10.1101/2020.10.26.355115 bioRxiv
Show abstract

The quantification of behaviors of interest from video data is commonly used to study brain function, the effects of pharmacological interventions, and genetic alterations. Existing approaches lack the capability to analyze the behavior of groups of animals in complex environments. We present a novel deep learning architecture for classifying individual and social animal behavior, even in complex environments directly from raw video frames, while requiring no intervention after initial human supervision. Our behavioral classifier is embedded in a pipeline (SIPEC) that performs segmentation, identification, pose-estimation, and classification of complex behavior, outperforming the state of the art. SIPEC successfully recognizes multiple behaviors of freely moving individual mice as well as socially interacting non-human primates in 3D, using data only from simple mono-vision cameras in home-cage setups.

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