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Inferring spatially transient gene expression pattern from spatial transcriptomic studies

Kueckelhaus, J.; Ehr, J. v.; Ravi, V. M.; Will, P.; Joseph, K. M.; Beck, J.; Hofmann, U. G.; Delev, D.; Schnell, O.; Heiland, H. D.

2020-10-21 bioinformatics
10.1101/2020.10.20.346544 bioRxiv
Show abstract

Spatial transcriptomic is a technology to provide deep transcriptomic profiling by preserving the spatial organization. Here, we present a framework for SPAtial Transcriptomic Analysis (SPATA, https://themilolab.github.io/SPATA), to provide a comprehensive characterization of spatially resolved gene expression, regional adaptation of transcriptional programs and transient dynamics along spatial trajectories.

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