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Group Testing with Homophily to Curb Epidemics with Asymptomatic Carriers

de Belleville, L.-M. H.

2020-10-13 health policy
10.1101/2020.10.09.20210260 medRxiv
Show abstract

Contagion happens through heterogeneous interpersonal relations (homophily) which induce contamination clusters. Group testing is increasingly recognized as necessary to fight the asymptomatic transmission of the COVID-19. Still, it is plagued by false negatives. Homophily can be taken into account to design test pools that encompass potential contamination clusters. I show that this makes it possible to overcome the usual information-theoretic limits of group testing, which are based on an implicit homogeneity assumption. Even more interestingly, a multiple-step testing strategy combining this approach with advanced complementary exams for all individuals in pools identified as positive identifies asymptomatic carriers who would be missed even by costly exhaustive individual tests. Recent advances in group testing have brought large gains in efficiency, but within the bounds of the above cited information-theoretic limits, and without tackling the false negatives issue which is crucial for COVID-19. Homophily has been considered in the contagion literature already, but not in order to improve group testing.

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