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A population-based seroprevalence survey of severe acute respiratory syndrome coronavirus 2 infection in Beijing, China

Wang, X.; Gao, W.; Cui, S.; Zhang, Y.; Zheng, K.; Ke, J.; Lv, J.; Yu, C.; Sun, D.; Wang, Q.; Li, L.

2020-09-23 epidemiology
10.1101/2020.09.23.20197756 medRxiv
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BACKGOUNDThe spread of Coronavirus Disease 2019 (COVID-19) had been controlled in China. The seroprevalence of COVID-19 in Beijing has not been evaluated. METHODSIn April, residents in Beijing were randomly enrolled. Blood samples were collected and antibodies to SARS- CoV-2 were tested by two colloidal gold kits. All colloidal gold positive serums were then tested by Micro- neutralization assay. RESULTSNone of 2,184 residents participated was tested positive by micro-neutralization assay. The seroprevalence of COVID-19 in Beijing was estimated < 0.17%. CONCLUSIONSThe seroprevalence of COVID-19 was low in April suggesting that community-wide spread was prevented in Beijing.

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