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On the relationship between serial interval, infectiousness profile and generation time

2020-09-18 epidemiology Title + abstract only
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The timing of transmission plays a key role in the dynamics and controllability of an epidemic. However, observing the distribution of generation times (time interval between the points of infection of an infector and infectee in a transmission pair) requires data on infection times, which are generally unknown. The timing of symptom onset is more easily observed; the generation time distribution is therefore often estimated based on the serial interval distribution (distribution of time interva...

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