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Influenza season 2019: analysis of 143 hospitalized cases

Carboni Bisso, I.; Prado, E.; Cantos, J.; Masso, A.; Staneloni, I.; San Roman, E.; Huespe, I.; Las Heras, M.

2020-09-18 intensive care and critical care medicine
10.1101/2020.09.16.20195974 medRxiv
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IntroductionInfluenza virus infection is a latent public health problem, affecting millions of people through the planet, and it is an important cause of morbidity and mortality. In Argentina, there is a significant absence of data regarding influenza severe respiratory disease and, therefore, a lack of knowledge about the impact of this disease at health institutions. ObjectivesAnalysis of clinical characteristics, image findings and laboratory variables in patients with influenza viruses during 2019. MethodsRetrospective, single-centre study, we analyzed all confirmed cases of influenza in a high complexity hospital from Buenos Aires. Results143 patients with influenza virus were hospitalized in this period of time. The 98.6% were infected by type A influenza, and most of them 61.5% were H1N1 subtype. Median age was 71 years (IQR 60 - 82), 77.6% were older than 70 years, and 88.1% had at least one coexisting illness. 39.1% of the patients required intensive care, 11.1% invasive mechanical ventilation and 4.1% died during hospitalization. ConclusionMortality and severity were similar to previous series of non-pandemic influenza. Analysis of annual data would be valuable in order to document the severity of influenza hospitalizations by ageJgroup and comorbidities according to the circulating influenza viruses.

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