In-silico modeling of COVID-19 ARDS: pathophysiological insights and potential management implications

2020-07-22 intensive care and critical care medicine Title + abstract only

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ObjectivesPatients with COVID-19 Acute Respiratory Distress Syndrome (CARDS) appear to present with at least two distinct phenotypes: severe hypoxemia with relatively well-preserved lung compliance and lung gas volumes (Type 1) and a more conventional ARDS phenotype displaying the typical characteristics of the baby lung (Type 2). We aimed to test plausible hypotheses regarding the pathophysiological mechanisms underlying CARDS, and to evaluate the resulting implications for ventilatory managem...

In-silico modeling of COVID-19 ARDS: pathophysiological insights and potential management implications

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