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Covid-19 and dysregulated cerebral perfusion: observations with multimodal MRI

Henry Feugeas, M.-C.; Gaudemer, A.; Lescure, X.; Dossier, A.; Sonneville, R.; Ehmer, C.; Choquet, C.; Israel, t.; Raynaud-Simon, A.; Borie, R.; Amarenco, P.; Khalil, A.

2020-07-14 radiology and imaging
10.1101/2020.07.12.20100941 medRxiv
Show abstract

The pathogenesis of encephalopathy-associated Covid-19 is still unclear. Multimodal brain MRI in 25 Covid-19 patients with neurological symptoms revealed angiographic and brain perfusion changes suggesting an under-recognized dysregulated brain perfusion not identified by morphological neuroimaging alone. Endothelial dysfunction, a key pathomechanism of dysregulated brain perfusion, may contribute to central-nervous-system disturbances in Covid-19.

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