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TMPRSS2 variants and their susceptibility to COVID-19: focus in East Asian and European populations.
2020-06-11
genetic and genomic medicine
Title + abstract only
View on medRxiv
Show abstract
The manifestation of the COVID-19 varies from absence of symptoms to Severe Acute Respiratory Syndrome. The epidemiological data indicate that infection and mortality rates are greater in European populations in comparison with eastern Asians. To test if epidemiological patterns may be partly determined by human genetic variation, we investigated, by exomic and databank analyses, the variability found in the TMPRSS2 gene in populations from different continents, since this gene is fundamental to...
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