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Monocyte class switch and hyperinflammation characterise severe COVID-19 in type 2 diabetes

2020-06-02 endocrinology Title + abstract only
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BackgroundEarly in the COVID-19 pandemic type 2 diabetes (T2D) was marked as a risk factor of severe disease and mortality. Inflammation is central to the aetiology of both conditions where variations in immune responses have the potential to mitigate or aggravate disease course. Identifying at risk groups based on immuno-inflammatory signatures is valuable in directing personalised care and developing potential targets for precision therapy. MethodsThis study characterised immunophenotypic var...

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