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SRY: An Effective Method for Sorting Long Reads of Sex-limited Chromosome

Wang, X.; Liu, Q.; Li, A.; Ruan, J.

2020-05-28 bioinformatics
10.1101/2020.05.25.115592 bioRxiv
Show abstract

Most of available reference genomes are lack of the sequence map of sex-limited chromosomes, that make the assemblies uncompleted. Recent advances on long reads sequencing and population sequencing raise the opportunity to assemble sex-limited chromosomes without the traditional complicated experimental efforts. We introduce a computational method that shows high efficiency on sorting and assembling long reads sequenced from sex-limited chromosomes. It will lead to the complete reference genomes and facilitate downstream research of sex-limited chromosomes.

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