SARS-CoV-2 detection in nasopharyngeal throat swabs by metagenomics
Tan, L. V.; Hong, N. T. T.; Ngoc, N. M.; Thanh, T. T.; Lam, V. T.; Nguyet, L. A.; Nhuc, L. N. T.; Ny, N. T. H.; Minh, N. N. Q.; Man, D. N. H.; Hang, V. T. T.; Khanh, P. N. Q.; Xuan, T. C.; Phong, N. T.; Tu, T. N. H.; Hien, T. T.; Hung, L. M.; Truong, N. T.; Yen, L. M.; Dung, N. T.; Thwaites, G.; Nguyen, C.
Show abstract
Metagenomics could detect SARS-CoV-2 in all eight nasopharyngeal/throat swabs with high/low viral loads, and rhinovirus in a co-infected patient. The sequenced viruses belonged to lineage B1. Because metagenomics could detect novel pathogen and co-infection, and generate sequence data for epidemiological investigation, it is an attractive approach for infectious-disease diagnosis.
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