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Risks and etiology of bacterial vaginosis revealed by species dominance network analysis
2020-05-26
obstetrics and gynecology
Title + abstract only
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BV (bacterial vaginosis) influences 20-40% of women but its etiology is still poorly understood. An open question about the BV is which of the hundreds of bacteria found in the human vaginal microbiome (HVM) are the causal pathogens of BV? Existing attempts to identify them have failed for at least two reasons: (i) a focus on species per se that ignores species interactions; (ii) a lack of systems-level understanding of the HVM. Here, we recast the question of microbial causality of BV by asking...
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