Comment on 'Initiation of chromosome replication controls both division and replication cycles in E. coli through a double-adder mechanism'
Le Treut, G.; Si, F.; Li, D.; Jun, S.
Show abstract
Witz et al. recently performed single-cell mother machine experiments to track growth and the replication cycle in E. coli. They analyzed the correlation structure of selected parameters using both their data and published data, and concluded that E. coli cell-size control is implemented at replication initiation, which challenged the newly emerged division-centric mechanism of cell-size control in bacteria. We repeated Witz et al.s analysis, and performed additional experiments and analytical calculations. These results explain Witz et al.s observation and in fact support the division-centric model.
Matching journals
The top 6 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- A Population Model Reveals Surprising Role of Stochastic Cell Division in Epigenetic Memory Systems 95%
- Investigating Local Negative Feedback of Rac Activity by Mathematical Models and Cell Motility Simulations 95%
- Mathematical Modeling and Analysis of Mitochondrial Retrograde Signaling Dynamics 95%
Similar papers in this journal
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.