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Submodular sketches of single-cell RNA-seq measurements

Yang, W.; Schreiber, J.; Bilmes, J.; Noble, W. S.

2020-05-03 bioinformatics
10.1101/2020.05.01.066738 bioRxiv
Show abstract

Analyzing and sharing massive single-cell RNA-seq data sets can be facilitated by creating a "sketch" of the data--a selected subset of cells that accurately represent the full data set. Using an existing benchmark, we demonstrate the utility of submodular optimization in efficiently creating high quality sketches of scRNA-seq data.

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