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Effective Heat Inactivation of SARS-CoV-2

Wang, T.; Lien, C.; Liu, S.; Selveraj, P.

2020-05-05 infectious diseases
10.1101/2020.04.29.20085498 medRxiv
Show abstract

In this study, we aimed to evaluate the stability of SARS-CoV-2 under four different heat conditions (37, 42, 56, 60 {degrees}C) and report that the virus is stable at 37 {degrees}C for at least 24 hours. Heating at 56 {degrees}C for 30 minutes, however, effectively inactivated the virus while preserved the stability of viral RNA in both human sera and sputum samples. These findings provide critical information regarding the biology of the virus as well as a practical way to inactivate infectious virus that is potentially found in clinical specimens.

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