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Sharing of weak signals of positive selection across the genome

Harris, N. S.; Rogers, A. R.

2020-04-24 genomics
10.1101/2020.04.22.055954 bioRxiv
Show abstract

Selection in humans often leaves subtle signatures at individual loci. Few studies have measured the extent to which these signals are shared among human populations. Here a new method is developed to compare weak signals of selection in aggregate across the genome using the 1000 Genomes Phase 3 Data. Results presented here show that selection producing weak selection serves to increase population differences around coding areas of the genome.

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