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Genomic regions linked to soft sweeps approximate neutrality when inferring population history from site pattern frequencies

Harris, N. S.; Rogers, A. R.

2020-04-23 genomics
10.1101/2020.04.21.053629 bioRxiv
Show abstract

Recent studies have suggested that selection is widespread throughout the genome and largely uncompensated for in inferences of population history. To address this potential issue, we estimated site pattern frequencies for neutral and selection associated areas of the genome. There are notable differences in these frequencies between neutral regions and those affected by selection. However, these differences have relatively small effects when inferring population history.

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