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Estimates of COVID-19 case-fatality risk from individual-level data

Bignami, S.; Ghio, D.; Van Assche, A.

2020-04-22 infectious diseases
10.1101/2020.04.16.20067751 medRxiv
Show abstract

When calculated from aggregate data on confirmed cases and deaths, the case-fatality risk (CFR) is a simple ratio between the former and the latter, which is prone to numerous biases. With individual-level data, the CFR can be estimated as a true measure of risk as the proportion of incidence for the disease. We present the first estimates of the CFR for COVID-19 by age and sex based on event history modelling of the risk of dying among confirmed positive individuals in the Canadian province of Ontario, which maintains one of the few individual-level datasets on COVID-19 in the world.

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