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Effectiveness Of Baseline And Post-Processed Chest X-Ray In Nonearly COVID-19 Patients

Gaeta, M.; Cicero, G.; Marino, M. A.; D'Angelo, T.; Mormina, E. M.; Mazziotti, S.; Blandino, A.; Siracusano, G.; La Corte, A.; Chiappini, M.; Finocchio, G.

2020-04-17 radiology and imaging
10.1101/2020.04.16.20061044 medRxiv
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BackgroundCT is a very sensitive technique to detect pneumonia in COVID-19 patients. However, it is impaired by high costs, logistic issues and high risk of exposure. Chest x-ray (CXR) is a low-cost, low-risk, not time consuming technique and is emerging as the recommended imaging modality to use in COVID-19 pandemic. This technique, although less sensitive than CT-scan, can provide useful information about pulmonary involvement. PurposeTo describe chest x-ray features of COVID-19 pneumonia and to evaluate the sensitivity of this technique in detecting pneumonia. A further scope is to assess the effectiveness of a post-processing algorithm in improving lung lesions detectability. Materials and Methods72 patients with laboratory-confirmed COVID-19 underwent bedside chest X-ray. Two radiologists were asked to express their opinion about: (i) presence of pneumonia (negative or positive); (ii) localization (unilateral or bilateral); (iii) topography (according to pulmonary fields); (iv) density (non consolidative ground-glass or inhomogeneous opacities; consolidative nodular-type or triangular; mixed consolidative e non-consolidative); and (v) presence of pleural effusion. The point (i) was evaluated separately, while the other points in consensus. A quality assessment of post-processed x-ray images was performed by two different readers. ResultsThe agreement about presence of pneumonia was almost perfect with K value of 0.933 and p < 0.001. Sensitivity was 69%. The following findings were seen: unilateral lung involvement in 50%; lower lung lesions in 54%; peripheral distribution in 48%; and non-consolidative pattern in 44%. Post-processed images improved the detection of lesions in 7 out 72 patients ({cong}10%) ConclusionCXR owns a good sensitivity in detecting COVID-19 lung involvement. Use of post-processing algorithm can improve detection of lesions. Our data support recommendations of the Radiological Society of North America (RSNA) to consider chest x-ray as first step imaging examination in Covid-19 patients. SUMMARYBedside CXR has a good sensitivity in evaluating COVID-19 lung involvement in hospitalized patients and should be considered as the first step imaging technique according to RSNA recommendations. KEY RESULTSO_LIBedside CXR has a good sensitivity in evaluating COVID-19 lung involvement in non-early clinical cases. C_LIO_LIThe most common findings of lung involvement were slight different from the well-described CT-ones, with less common patterns of bilateral and peripheral distribution. C_LIO_LIPost-processing algorithm enhances detection of pulmonary lesions. C_LI

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