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Auditory features modelling demonstrates sound envelope representation in striate cortex

Martinelli, A.; Handjaras, G.; Betta, M.; Leo, A.; Cecchetti, L.; Pietrini, P.; Ricciardi, E.; Bottari, D.

2020-04-17 neuroscience
10.1101/2020.04.15.043174 bioRxiv
Show abstract

The striate cortex is no longer considered exclusively visual in its function. Proofs that its activity is modulated by acoustic inputs have accrued. By employing category-based and feature modeling approaches, here we characterized V1 activity (in absence of retinal input) during the processing of natural and synthetically derived sounds. First, we showed that distinct sound categories could be dissociated by the analysis of V1 multivoxel response patterns. Hence, we assessed whether a hallmark of sound neural representations is mapped in V1. In each sound category, we modeled sound envelopes and assessed whether these were represented at the single-voxel level in the striate cortex and, as a control, in the temporal cortex. The hierarchical organization of sound categories allowed to exert control over dimensions that could spuriously lead to sound envelope V1 mapping. Variations of sound amplitude over time were successfully decoded in V1 regardless of the category class. Results confirm that the human striate cortex receives acoustic category-based input and demonstrate that V1 is a genuine locus of sound envelope representation.

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