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Delivering oxygen-enriched CPAP respiratory support using a non-invasive ventilation device

Culmer, P.; Ashton, S.; Latham, M.; Murdoch, S.; Brettle, D.; Kapur, N.

2020-04-11 respiratory medicine
10.1101/2020.04.06.20055665 medRxiv
Show abstract

The COVID-19 pandemic has placed a dramatic increase in demand on healthcare providers to provide respiratory support for patients with moderate to severe symptoms. In conjunction, the pandemic has challenged existing supply-chains to meet demands for medical equipment and resources. In response to these challenges, we report our work to repurpose two existing non-invasive ventilation (NIV) systems to provide solutions for the delivery of oxygen-enriched CPAP ventilation which are inherently resource and oxygen-efficient. We consider adaptation of CPAP systems typically used for sleep apnoea, together with a new Venturi-valve design which can be readily produced through 3D printing. Our aim in both cases was to support Positive end-expiratory pressure (PEEP) of [≥]10cmH2O while achieving [≥]40% FiO2. This supports a crucial part in the patient pathway for COVID-19 treatment, helping to provide early respiratory support prior to invasive ventilation options in the ICU.

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