Back
Top 0.5%
11.1%
Top 0.9%
11.1%
Top 61%
9.1%
Top 2%
7.9%
Top 0.6%
6.5%
#1
6.5%
Top 15%
6.5%
Top 0.9%
5.1%
Top 2%
3.9%
Top 1%
2.8%
Top 2%
2.0%
Top 6%
2.0%
Top 80%
2.0%
Top 0.6%
1.5%
Top 0.4%
1.5%
Top 7%
1.4%
Top 8%
1.4%
Top 2%
1.2%
Top 2%
0.7%
Top 1%
0.7%
Top 10%
0.7%
Top 12%
0.7%
Top 7%
0.7%
Blind Uneven Proliferation of CD4+ T cells During Primary Infection Generates the Majority of the HIV Reservoir
2020-04-10
hiv aids
Title + abstract only
View on medRxiv
Show abstract
The HIV reservoir is a population of 1-10 million anatomically dispersed, latently infected memory CD4+ T cells in which an HIV DNA molecule is quiescently integrated into human chromosomal DNA. When antiretroviral therapy (ART) is stopped and HIV replication initiates in one of these cells, systemic viral spread resumes, rekindling progression to AIDS. Therefore, HIV latency prevents cure. The HIV reservoir contains clones: identical HIV sequences that are integrated within identical human chro...
Predicted journal destinations
1
AIDS
25 training papers
2
eLife
262 training papers
3
PLOS ONE
1737 training papers
4
PLOS Computational Biology
141 training papers
5
Proceedings of the National Academy of Sciences
100 training papers
6
PLOS Pathogens
35 training papers
7
Nature Communications
483 training papers
8
JAIDS Journal of Acquired Immune Deficiency Syndromes
18 training papers
9
JCI Insight
63 training papers
10
Journal of the International AIDS Society
19 training papers
11
Journal of The Royal Society Interface
54 training papers
12
The Journal of Infectious Diseases
137 training papers
13
Scientific Reports
701 training papers
14
Frontiers in Microbiology
36 training papers
15
Virus Evolution
26 training papers
16
Nature Medicine
88 training papers
17
Epidemics
96 training papers
18
Science Advances
52 training papers
19
Cell
28 training papers
20
EBioMedicine
21 training papers
21
Viruses
79 training papers
22
eBioMedicine
82 training papers
23
Communications Medicine
63 training papers